novaluron

Molecular Structure

Activity

Insecticide.Novaluron is a chitin synthase inhibitor active against larvae of the orders Coleoptera, Homoptera, Diptera and Lepidoptera. Chitin is only actively synthesised by the immature stages of insects resulting in good selectivity to adults of beneficial species. Novaluron is strictly a contact insecticide; it has no systemic activity. It is mainly a stomach poison and has some ovicidal activity.
A further mode of action for novaluron was reported in 2002 (BCPC) - it was found to be an inhibitor of acetylcholinesterase in B-biotype Bemisia tabaci, similar to buprofezin, another chitin synthesis inhibitor. This could indicate that there is cross-resistance between novaluron and buprofezin. No cross-resistance has been noted between novaluron and other benzoyl urea IGR’s used against Bemisia tabaci, Spodoptera spp and Leptinotarsa.
In field trials on cotton and vegetables, novaluron has shown residual activity lasting at least 15 days.
Novaluron is reported to damage the leaves of poinsettias (chlorotic streaking or blotching); Crompton does not recommend its use on this ornamental species.
In Ontario (Canada), novaluron is under evaluation by Crompton and the University of Guelph for control of Colorado beetle on potato; this pest is rapidly developing resistance to the currently used insecticides. Initial results (2002) were promising with novaluron maintaining the populations of 3rd and 4th instar larvae at the level of the industry reference (imidacloprid).
In field and laboratory trials, the product was found to be safe to major beneficial insects and can be used as a part of the IPM programme. In order to preserve its effectiveness, use of the product should be restricted to two applications per season in alternation with other products.

CropUses:
apples, aubergines, cabbage, Chinese cabbage, citrus, cotton, eggs, forestry, maize, meat, milk, ornamentals, pears, pome fruits, potatoes, stone fruits, tobacco, tomatoes, tree fruits, turf, vegetables

Premix

Physical Properties

Molecular weight:492.7g/mol; Density:1.56 (22°C); Composition:Tech. is 96%. Melting point:176.5-178°C; Flash point:202°C (closed cup) (EEC A9, ASTM E502-84 and ASTM D 32786-82); Vapour pressure:1.6 × 10-2 mPa (25°C) (OECD 104, EEC A8); Partition coefficient(n-octanol and water):logP = 4.3 (OECD 107, EEC A4); Solubility:In water 53.07 mg/l (25 °C) (OECD 105, EEC A6). Soluble in organic solvents.;

Toxicology

Oral:Acute oral LD50 for rats >5000 mg/ kg. Percutaneous:Acute percutaneous LD50 for rats >2000 mg/kg. Not irritating to eyes and skin (rabbits). Not a skin sensitiser (guinea pigs). Inhalation: LC50 (4 h) for rats >5.15 mg/l air. ADI:(US) 0.02 mg/ kg b.w.

Environmental Profile

Ecotoxicology:
Algae:Non-toxic.Bees: LC50 (oral and contact) >100 mg/bee.Birds:Acute oral LD50 for mallard ducks >2000 mg/kg. Dietary LC50 (5 d) for bobwhite quail and mallard ducks >5200 ppm.Daphnia: LC50 (48 h) 58 mg/l.Fish: LC50 (96 h) for rainbow trout and bluegill sunfish >1 mg/l.Worms:Non-toxic.Other beneficial spp.:Non-toxic.
Environmental fate:
Animals:The major route of elimination was via the faeces.Soil: DT50 (aerobic) 68.5-75.5 d (sandy loam and loamy sand soils). Strongly adsorbed to soil, Koc 6650-11 813.Plant:In potatoes and apples, a.i. remains unchanged.

Transport Information

Signal Word:CAUTION; Hazard Class:III(Slightly hazardous)

Yantai Keda Chemical Co., Ltd. was founded in November 1999 and is situated in Zhaoyuan, the Gold Capital of China, a subsidiary of Shandong Jindu Construction Group, which is a comprehensive group company integrating real estate, construction, building materials, chemicals and rubber, with a registered capital of RMB 150 million, current fund of RMB 130 million and fixed assets of RMB 500 million. The group is also listed in “Yantai Top 100 Enterprises”.
Supported by powerful capital strength, the company had a registered capital of RMB 10 million when it was initially established but now has fixed assets of RMB 12 million and current capital of RMB 20 million. The company covers an area of 35,000 m2 and has a construction area of 7,500 m2.
The company focuses on talent cultivation. At present, it has 168 employees, including 35 professional engineers and technicians and 22 with intermediate or higher titles. It also regards science and technology as the motive power and establishes formal cooperative relation in “Production, Study, Research” with Shandong University. The company set up Keda Chemical Research Institute, which has 17 full-time researchers, of whom 7 have intermediate and senior titles and 5 have the bachelor and master degrees. Every year, the company invests nearly RMB 1 million in research. It also employs many senior engineers and senior agronomists from Shenyang Chemical Research Institute, Shandong Academy of Agricultural Sciences, Shandong Agricultural University and Shandong Pesticide Research Institute to assume its technical consultants.
What’s more, the company also boasts superior production equipment, a complete quality assurance system and complete quality detection measures, which lay a good foundation for the development of pesticides. Now, the company has 2 kinds of raw pesticides, 5 forms and 18 products, and achieves an annual output value of RMB 50 million. The company is the first and largest raw profenofos and pyrimethanil manufacturer in China. The raw pesticides now are exported to India, Pakistan, Africa and other countries and regions, the quality of the products are deeply trusted by customers!

WELCOME TO OUR FACTORY!