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Pharmaceutical Chemicals, Tretinoin, Retinoic Acid, 302-79-4

Location:
Xi'an, China ( Mainland)
Status:
New
Sample Availibility:
yes
Payment Terms:
Cash, Bank Transfer, Letter of Credit, T/T, L/C
Categories:
Home > Health & Beauty > Pharmaceutical Chemicals

Product Description

Tretinoin

Introduction

Product Name:

Tretinoin (Retinoic acid)

Appearance :

yellow or light orange crystalline powder

Cas:

302-79-4

Molecular formula:

C20H28O2

Molecular weight :

300.44

Supplier name:

xi’an Wison biological technology co.,ltd

Synonyms:

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid;

all-trans-Retinoic acid; Vitamin A acid; Retionoic Acid; Tretinoin (Retionoic Acid); Tretinion ;

N,N'-hexane-1,6-diyldiacetamide; retinoic acid; (9cis)-retinoic acid;

(11cis,13cis)-7,8-dihydroretinoic acid; 15-oxidoretinal

Specification

98.0~102.0%

Structure

Function

1 Tretinoin is the acid form of vitamin A and is also known as all-trans retinoic acid or ATRA. It is a drug commonly used to treat acne vulgaris and keratosis pilaris. It is available as a cream or gel It is also used to treat acute promyelocytic leukemia, and is sold for this indication by Roche under the brand name Vesanoid. It is also available as a generic.

2 Its success in treating acute promyelocytic leukemia was a major breakthrough in the treatment of this type of leukemia.It works in APL because the majority of cases involve a chromosomal translocation of chromosomes 15 and 17, which causes genetic fusion of the retinoic acid receptor gene to the promyelocytic leukemia gene. This fusion PML-RAR protein is responsible for preventing immature myeloid cells from differentiating into more mature cells. This block in differentiation is thought to cause leukemia. ATRA acts on PML-RAR to lift this block, causing the immature promyelocytes to differentiate to normal mature blood cells thus decreasing promyelocytes.

Specification

Test/Observation

Specifications

Result

Assay Content

98%-102%

99.72%

Appearance

Yellow Powder

Complies

Identification A

B

UV

IR

Complies

Complies

Residue on ignition

MAX 0.1%

Complies

Loss on drying

MAX 0.5%

0.39%

Ash

MAX.1.0%

0.52%

Heavy Metals PPM

MAX.20PPM

Complies

As

Max. 2 PPM

Complies

Pb

Max. 1 PPM

Complies

Hg

Max. 1 PPM

Complies

Limit of Isotretinoin

MAX5.0%

2.9%

Organic Volatile Impurities

Meet The Requirements

Complies

Package & Storage:

Packing: By 25kgs/drum, inner by double plastic bag.

Storage: Stored in a cool&dry well-closed container, keep away from moisture and strong light/heat.

Shelf life: Two years under well storage situation.

About Us:

Xian Wison Biological Technology Co.,Ltd. locates in ecological zone and business center, We specialize in manufacturing all kinds of natural herb extract, natural food additive, pharmaceutical intermediate, daily chemical products as well as technology research, transfer and consultation of food, drink,cosmetic, medicine and healthy product.

Our GMP production base locates in Sanyuan of Shaanxi, with the yearly capacity of 1000 ton based on exceptional botanical natural resource. We have established a independent R&D centre in Xi’an High-Tech Development Zone. We have high performance liquid chromatography, gas chromatography, Atomic Absorption Spectrometer, Ultra-violet and Visible Spectrophotometer, and analysis appliances of micro-organism Lab. Moreover, we have another process-scale chromatography production line which specializes in manufacturing high purity natural botanical ingredients.

Other:

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Contact Information

Company:
 Xi'an Wison Biological Technology Co., Ltd.
Phone Number:
  86-29-86100035
Fax Number:
 86-29-83340290
 
Xi'an Wison Biological Technology Co., Ltd.
 Shaanxi , China FREE
 

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