Salinomycin pharm 12% premix

Salinomycin is a polyether antibiotic from the group of ionophores. It exerts anticoccidial effect against all species known as causative agents of coccidiosis in poultry (Eimeria acervulina, E. maxima, E. necatrix, E. mivati, E. tenella, E. brunetti) as well as in the other farm animals (E. meleagridis, E. meleagrimitis, E. bovis, etc.). It is active against Gram-positive microorganisms, some anaerobes and Serpulina (Treponema) hyodysenteriae. The biological activity of salinomycin is based on its ability to form lipophilic complexes with the monovalent alkaline ions, making the cellular membranes of coccidia permeable to the ions mentioned. In this way, the intracellular ion concentration in the parasite cells is disturbed and anticoccidial effect of the preparation is achieved. This action is manifested already at the earliest stage of coccidia development hindering the maturity of the schizonts and the development of merozoites. An additional influence is the impeded transport of carbohydrate and the active sporozoite glycolysis provoked by salinomycin. The administration of salinomycin with the feed to ruminants (with developed forestomachs) at the recommended concentrations improves the weight gain and the feed conversion efficiency of the animals (as a result of the influence on the microflora and microfauna in the forestomachs which leads to an increase in the concentration of propionic acid and a decrease in the concentrations of lactic acid and acetic acid and a diminution of methane eructation from the rumen). Salinomycin reveals a nutritive effect in the growing and fattening pigs as well (affecting positively the beneficial microflora in the digestive tract of the animals).

For prevention of coccidiosis in poultry (chickens for fattening and chickens reared for laying up to 12 weeks of age) caused by Eimeria tenella, E. acervulina, E. mivati, E. maxima, E. necatrix. For improvement of weight gain and feed conversion efficiency in pigs and ruminants with developed forestomachs (calves and lambs) for fattening.

Medicated feed, supplemented with salinomycin and intended for chickens, must not be given to laying hens, guinea hens and to horses and other equine species in particular. The preparation is incompatible with tiamulin (animals must not be treated with salinomycin for at least seven days before and after receiving feed containing tiamulin).

Orally, thoroughly mixed into feed.

In order to reach uniform homogenization with feed, it is recommended to mix the measured quantity of the preparation (calculated on the basis of the prescribed dose) on stages in the following order: up to 10 kg feed; up to 100 kg feed; and up to 1000 kg final feed.

Chickens, pigs, calves, lambs.

SPECIES

Salinomycin sodium ppm

Salinopharm 12% premix g/ ton feed

For meat:

Chickens for fattening - 5 (five) days after the last administration of the product.

Calves, lambs, pigs - 0 (zero) days.

Replacement layers up to 12 weeks of age - 5 (five) days.

In the original packing, well closed, in dry and well-ventilated facilities, protected from direct sunlight at temperature between 15° and 25°C.